"Coco's still struggling," Melvin said. "He's definitely got it the worst. I guess there are different degrees of it, but I guess Coco's the one who hasn't gotten any better."
Catcher Kurt Suzuki, who was also touched by the contagious bug, remained in the lineup for the finale against the Angels, while Josh Reddick resumed right-field duties one day after transferring to the designated hitter spot as a result of being slightly under the weather.
"It's like kindergarten," joked Melvin, who has been carrying around a bottle of Purell sanitizer in his back pocket. "Wash your hands, do the best you can."
With Crisp still sidelined, Jonny Gomes received his second straight start in left field. The A's veteran hit his third homer of the season -- which have accounted for all of his hits -- on Wednesday.
The A's 12 long balls in their first 13 games are the most since 2006, when they hit 17.