"I feel good, but I'm sad because I didn't pitch the way I wanted," Cueto said via a translator.
Trouble started with one out in the second when Chris Young hit a one-out double and was followed by Derek Norris, who pushed a 1-0 pitch the opposite way for a two-run homer to right field -- his fourth home run of spring.
A two-out walk to Josh Donaldson hurt as Jemile Weeks hit a single which sent Donaldson to third. After a second walk to Eric Sogard, Jed Lowrie lined a single to center field, scoring Donaldson and Weeks. Josh Reddick added an RBI double to left-center field to finish Cueto's afternoon.
Cincinnati scored three runs in the bottom of the second against A's lefty Brett Anderson. With one out, Todd Frazier hit a two-run homer to right field on a 1-1 pitch. Derrick Robinson later hit an RBI double to right field with two outs to keep Cincinnati close.
Oakland scored twice in the third against Minor League righty Nick Christiani as Donaldson hit a two-run ground-rule double to right field. In the Reds' three-run fifth against Anderson, Robinson hit a solo homer to left-center field. There were two outs against Oakland reliever Mike Ekstrom when Chris Heisey and Zack Cozart each hit RBI singles.
Anderson was done after 4 2/3 innings, giving up six earned runs on eight hits with two walks and five strikeouts.
"The results weren't awesome, but I threw some good pitches. I threw some not good pitches. I threw a lot of pitches I wouldn't throw in a regular season game. A lot of changeups that got hit. I got some strikeouts on my slider that was good," said Anderson. "Today was more about focus, really. Anytime you get eight runs you lose focus. It's hard to get in a rhythm when you sit for a half hour.
"Next time I will try to pitch like it's a normal game."
Oakland closer Grant Balfour pitched a scoreless sixth in his Cactus League debut. He didn't surrender a hit or a walk and fanned one.
In the seventh, the Reds threatened as a one-run ground-rule double from Xavier Paul made the score 8-7. The A's scored two more in the next inning with a two-run double from Daric Barton, which held up.
The Reds made it 10-9 in the ninth on a solo home run from Denis Phipps off Travis Blackley.
Up next for A's: Jarrod Parker will get the ball when the A's host the White Sox at 7:05 p.m. PT at Phoenix Municipal Stadium. If he's in the lineup, Derek Norris will be trying for his third straight multi-hit game of spring.